Hepatoblastoma

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Case Series of Hepatoblastoma

Background: In the past 20 years, a dramatic improvement in the prognosis of patients with hepatoblastoma (HB)has been achieved by combining surgery and chemotherapy in several national and international trials.Materials and Methods: Four children ( 3 girl and 1 boy) aged 34 days, 4 months, 13 months, and 1 year with meanage of 6.53 (±5.15) months were presented to our center from 2002 to 2009 ...

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Hepatoblastoma: when to screen?

Introduction Hepatoblastoma is a rare hepatic malignancy that is seen in Familial Adenomatous Polyposis (FAP). The occurrence is four hundred fold higher than the general population [1]. Hepatoblastoma is generally treatable with surgery; in addition it is highly responsive to chemotherapy. While the literature reports on this extracolonic manifestation of FAP, no screening recommendations exis...

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Treatment of hepatoblastoma

In the early ‘80s the 5-overall-survival (OS) of children affected by HB was estimated to be on the 30% range. From the late ‘80s with the introduction of Cisplatin (CDDP) based CT regimen a dramatic change in the prognosis of these young patients was started to be documented. The first reports on the effect of this drug on HB regarded relapsing or resistant HB to the conventional CT of those y...

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Childhood cancers: hepatoblastoma.

Hepatoblastoma is the most common primary liver tumor in children, accounting for just over 1% of pediatric cancers. The etiology is unknown, but it has been associated with Beckwith-Weidemann syndrome, familial adenomatosis polypi, and low birth weight. The primary treatment is surgical resection, however, chemotherapy plays an important role by increasing the number of tumors that are resecta...

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Mesenchymal Hamartoma Mimicking Hepatoblastoma

Mesenchymal hamartoma and hepatoblastoma are common causes of hepatic masses in pediatric population; they have similar radiologic and pathologic features. Herein, we present a case of mesenchymal hamartoma that was preoperatively diagnosed as hepatoblastoma. The mass was completely resected instead of being treated with preoperative chemotherapy. Postoperative pathological evaluation revealed ...

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ژورنال

عنوان ژورنال: HPB

سال: 2019

ISSN: 1365-182X

DOI: 10.1016/j.hpb.2019.10.2398